Gout is caused by a build-up of uric acid in the body, which leads to the development of sharp acid crystal deposits in joints. It’s usually the big toe that is most commonly affected by gout but it can also affect the wrists, fingers, ankles, and elbows. In some cases, the pain from gout is so severe and even something as light as a bed sheet can cause sharp pain that can last for weeks at a time. Read more here.